Combining nucleotide variations and structure variations for improving astaxanthin biosynthesis.

ABSTRACT:

Background

Mutational technology has been used to achieve genome-wide variations in laboratory and industrial microorganisms. Genetic polymorphisms of natural genome evolution include nucleotide variations and structural variations, which inspired us to suggest that both types of genotypic variations are potentially useful in improving the performance of chassis cells for industrial applications. However, highly efficient approaches that simultaneously generate structural and nucleotide variations are still lacking.

Results

The aim of this study was to develop a method of increasing biosynthesis of astaxanthin in yeast by Combining Nucleotide variations And Structure variations (CNAS), which were generated by combinations of Atmospheric and room temperature plasma (ARTP) and

SUBMITTER: Jin J 

PROVIDER: S-EPMC9082887 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature