Gadolinium-labelled iron/iron oxide core/shell nanoparticles as T ₁-T ₂ contrast agent for magnetic resonance imaging.

ABSTRACT: Magnetic resonance imaging (MRI) is indispensable and powerful in modern clinical diagnosis and has some advantages such as non-invasiveness and high penetration depth. Furthermore, dual T ₁-T ₂ MR imaging has attracted crucial interest as it can decrease the risk of pseudo-positive signals in diagnosing lesions. And it's worth nothing that the dual-mode MR imaging displays a vital platform to provide relatively comprehensive diagnosis information and receive accurate results. Herein, we report a dual T ₁-T ₂ MR imaging contrast agent (CA) grounded on the iron/iron oxide core/shell nanomaterials conjugated with gadolinium chelate. The Gd-labeled Fe@Fe₃O₄ NPs reveal the feasibility to utilize them

SUBMITTER: Wang K 

PROVIDER: S-EPMC9083088 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature