Study designs for clinical trials applied to personalised medicine: a scoping review.

ABSTRACT:

Objective

Personalised medicine (PM) allows treating patients based on their individual demographic, genomic or biological characteristics for tailoring the 'right treatment for the right person at the right time'. Robust methodology is required for PM clinical trials, to correctly identify groups of participants and treatments. As an initial step for the development of new recommendations on trial designs for PM, we aimed to present an overview of the study designs that have been used in this field.

Design

Scoping review.

Methods

We searched (April 2020) PubMed, Embase and the Cochrane Library for all reports in English, French, German, Italian and Spanish, describing study designs for clinical trials applied to PM. Study selection and data extraction were performed

SUBMITTER: Superchi C 

PROVIDER: S-EPMC9083424 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature