Vapor exposure to Δ9-tetrahydrocannabinol (THC) slows locomotion of the Maine lobster (Homarus americanus).

ABSTRACT:

Rationale

Despite a long history of use in synaptic physiology, the lobster has been a neglected model for behavioral pharmacology. A restaurateur proposed that exposing lobster to cannabis smoke reduces anxiety and pain during the cooking process. It is unknown if lobster gill respiration in air would result in significant Δ⁹-tetrahydrocannabinol (THC) uptake and whether this would have any detectable behavioral effects.

Objective

The primary goal was to determine tissue THC levels in the lobster after exposure to THC vapor. Secondary goals were to determine if THC vapor altered locomotor behavior or nociception.

Methods

Tissue samples were collected (including muscle, brain and hemolymph) from Homarus americanus (N = 3 per group) following 30 or 60 min of

SUBMITTER: Gutierrez A 

PROVIDER: S-EPMC9083469 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature