One-step synthesis of amino-functionalized up-converting NaYF₄:Yb,Er nanoparticles for in vitro cell imaging.

ABSTRACT: The emerging up-conversion nanoparticles (UCNPs) offer a wide range of biotechnology applications, from biomarkers and deep tissue imaging, to single molecule tracking and drug delivery. Their successful conjugation to biocompatible agents is crucial for specific molecules recognition and usually requires multiple steps which may lead to low reproducibility. Here, we report a simple and rapid one-step procedure for in situ synthesis of biocompatible amino-functionalized NaYF₄:Yb,Er UCNPs that could be used for NIR-driven fluorescence cell labeling. X-ray diffraction showed that UCNPs synthesized through chitosan-assisted solvothermal processing are monophasic and crystallize in a cubic α phase. Scanning and transmission electron microscopy revealed that the obtained cryst

SUBMITTER: Mancic L 

PROVIDER: S-EPMC9083799 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature