Fabrication of an activatable hybrid persistent luminescence nanoprobe for background-free bioimaging-guided investigation of food-borne aflatoxin in vivo.

ABSTRACT: The development of in situ and real-time analytical methods for specifically probing food-borne hazardous substances is promising for clarifying their harmful behaviors and related disease mechanisms inside the living body through in situ investigation of their in vivo behaviors. Herein, optical nanoimaging with the ability of in situ non-damage detection and real-time monitoring was introduced for specific recognition of aflatoxin in cellular levels and in vivo via the fluorescence resonance energy transfer (FRET) protocol. Persistent luminescence nanophosphors (PLNPs) with distinct advantages of improved sensitivity and signal-to-noise ratio were employed in in vivo bioimaging as photoluminescence nanoprobes, while copper sulfide nanoparticles we

SUBMITTER: Liu JM 

PROVIDER: S-EPMC9084300 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature