Long-term Outcomes of Salvage Lymph Node Dissection for Nodal Recurrence of Prostate Cancer After Radical Prostatectomy: Not as Good as Previously Thought.

ABSTRACT:

Background

Long-term outcomes of patients treated with salvage lymph node dissection (sLND) for nodal recurrence of prostate cancer (PCa) remain unknown.

Objective

To investigate long-term oncological outcomes after sLND in a large multi-institutional series.

Design, setting, and participants

The study included 189 patients who experienced prostate-specific antigen (PSA) rise and nodal-only recurrence after radical prostatectomy (RP) and underwent sLND at 11 tertiary referral centers between 2002 and 2011. Lymph node recurrence was documented by positron emission tomography/computed tomography (PET/CT) scan using either ¹¹C-choline or ⁶⁸Ga prostate-specific membrane antigen ligand.

Outcome measurements and statistical analysis

The primary

SUBMITTER: Bravi CA 

PROVIDER: S-EPMC9084633 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature