Identifying the Optimal Candidate for Salvage Lymph Node Dissection for Nodal Recurrence of Prostate Cancer: Results from a Large, Multi-institutional Analysis.

ABSTRACT:

Background

Salvage lymph node dissection (SLND) represents a possible treatment option for prostate cancer patients affected by nodal recurrence after local treatment. However, SLND may be associated with intra- and postoperative complications, and the oncological benefit may be limited to specific groups of patients.

Objective

To identify the optimal candidates for SLND based on preoperative characteristics.

Design, setting, and participants

The study included 654 patients who experienced prostate-specific antigen (PSA) rise and nodal recurrence after radical prostatectomy (RP) and underwent SLND at nine tertiary referral centers. Lymph node recurrence was documented by positron emission tomography/computed tomography (PET/CT) scan using either ¹¹C-choline

SUBMITTER: Fossati N 

PROVIDER: S-EPMC9084635 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature