A novel pyrazolo[1,5-a]pyridine fluorophore and its application to detect pH in cells.

ABSTRACT: A new fluorescent probe based on pyrazolo[1,5-a]pyridine was synthesized and used to monitor the pH in cells. This probe exhibited a fast response to acidic pH (less than 10 s), a high quantum yield (φ = 0.64), and high selectivity and sensitivity. The response mechanism of the fluorescent probes relies on the ICT change.

SUBMITTER: Zhang P 

PROVIDER: S-EPMC9085528 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature