Risk factors for nephropathy in persons with type 1 diabetes: a population-based study.

ABSTRACT:

Aims

Albuminuria is strongly associated with risk of renal dysfunction, cardiovascular disease and mortality. However, clinical guidelines diverge, and evidence is sparse on what risk factor levels regarding blood pressure, blood lipids and BMI are needed to prevent albuminuria in adolescents and young adults with type 1 diabetes.

Methods

A total of 9347 children and adults with type 1 diabetes [mean age 15.3 years and mean diabetes duration 1.4 years at start of follow-up] from The Swedish National Diabetes Registry were followed from first registration until end of 2017. Levels for risk factors for a risk increase in nephropathy were evaluated, and the gradient of risk per 1 SD (standard deviation) was estimated to compare the impact of each risk factor.

Results

Dur

SUBMITTER: Seyed Ahmadi S 

PROVIDER: S-EPMC9085666 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature