Assessment of the prognostic value of SPOCK1 in clear cell renal cell carcinoma: a bioinformatics analysis.

ABSTRACT:

Background

Clear cell renal cell carcinoma (ccRCC) is one of the most common urological malignancies, and once metastasis occurs, it often has a poor prognosis and lacks effective treatment. Therefore, there is an urgent need to screen some new biomarkers and explore their molecular mechanisms to improve the early clinical diagnosis and targeted therapy of ccRCC. SPOCK1 (SPARC/osteonectin, CWCV and Kazal-like domains proteoglycan 1) is a conserved multi-domain proteoglycan that plays an important role in the development of multiple cancer types; however, its prognostic value in ccRCC has not been investigated. The study of the prognostic value of SPOCK1 in ccRCC is a good complement to the study of ccRCC biomarkers.

Methods

Databases of this study included Onco

SUBMITTER: Chen J 

PROVIDER: S-EPMC9085920 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature