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KI-catalyzed oxidative cyclization of α-keto acids and 2-hydrazinopyridines: efficient one-pot synthesis of 1,2,4-triazolo[4,3-a]pyridines.

ABSTRACT: A one-pot approach to substituted 1,2,4-triazolo[4,3-a]pyridines has been developed that is based on a KI-catalyzed oxidative cyclization of α-keto acids and 2-hydrazinopyridines. This transition-metal-free procedure was highly efficient and shows good economical and environmental advantages.

SUBMITTER: Yang DS

PROVIDER: S-EPMC9086216 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature

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KI-catalyzed oxidative cyclization of α-keto acids and 2-hydrazinopyridines: efficient one-pot synthesis of 1,2,4-triazolo[4,3-a]pyridines.

Yang De-Suo DS Wang Juan J Gao Peng P Bai Zi-Jing ZJ Duan Dong-Zhu DZ Fan Ming-Jin MJ

RSC advances 20180921 57

A one-pot approach to substituted 1,2,4-triazolo[4,3-a]pyridines has been developed that is based on a KI-catalyzed oxidative cyclization of α-keto acids and 2-hydrazinopyridines. This transition-metal-free procedure was highly efficient and shows good economical and environmental advantages. ...[more]

PMID: 35547701

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