Microfabricated passive resonator biochip for sensitive radiofrequency detection and characterization of glucose.

ABSTRACT: Passive sensors provide a new route for the characterization of concentration-dependent radiofrequency parameters with high reproducibility in real time. We propose a microfabricated resonator realized using integrated passive device technology for the sensitive detection and characterization of glucose. Experimental results verify the high performance of the proposed biosensor, because radiofrequency parameters such as resonance frequency (from 0.541 to 1.05 GHz) and reflection coefficient (from -34.04 to -24.11 dB) linearly vary in response to deionized water and subsequent iterative measurements of different glucose concentrations (from 50 to 250 mg dL^-1). The biosensor has a very low limit of detection of 8.46 mg dL^-1, a limit of quantitation of 25.63 mg dL^-1

SUBMITTER: Koirala GR 

PROVIDER: S-EPMC9086445 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature