The Nadir Oxygen-Specific Heart Rate Response in Sleep Apnea Links With the Occurrence of Acute Myocardial Infarction.

ABSTRACT:

Background

Little is known regarding the quantification of sleep apnea- and hypoxemia-elicited heart rate (HR) response and its prognostic significance of the cardiovascular risk. We sought to explore the impact of HR response and variability specific to obstructive sleep apnea (OSA) on the occurrence of a common cardiovascular event - acute myocardial infarction (AMI).

Methods

Consecutive patients with suspected OSA were enrolled and underwent nocturnal respiratory study and electrocardiography monitoring. The minimal oxygen saturation (minSpO₂) was determined from the oxygen saturation curve under a subject-specific search window. Primary HR metrics such as maximal HR in response to minSpO₂ and respiratory event-specific HR variability were computed f

SUBMITTER: Huang Z 

PROVIDER: S-EPMC9086507 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature