Spontaneous Water Radical Cation Oxidation at Double Bonds in Microdroplets.

ABSTRACT: Spontaneous oxidation of compounds containing diverse X=Y moieties (e.g., sulfonamides, ketones, esters, sulfones) occurs readily in organic-solvent microdroplets. This surprising phenomenon is proposed to be driven by the generation of an intermediate species [M+H₂O]^+·: a covalent adduct of water radical cation (H₂O ^+· ) with the reactant molecule (M). The adduct is observed in the positive ion mass spectrum while its formation in the interfacial region of the microdroplet (i.e., at the air-droplet interface) is indicated by the strong dependence of the oxidation product formation on the spray distance (which reflects the droplet size and consequently the surface-to-volume ratio) and the solvent composition. Importantly, based on the scre

SUBMITTER: Qiu L 

PROVIDER: S-EPMC9086510 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature