Sero-prevalence of 19 infectious pathogens and associated factors among middle-aged and elderly Chinese adults: a cross-sectional study.

ABSTRACT:

Objectives

To systematically assess the sero-prevalence and associated factors of major infectious pathogens in China, where there are high incidence rates of certain infection-related cancers.

Design

Cross-sectional study.

Setting

10 (5 urban, 5 rural) geographically diverse areas in China.

Participants

A subcohort of 2000 participants from the China Kadoorie Biobank.

Primary measures

Sero-prevalence of 19 pathogens using a custom-designed multiplex serology panel and associated factors.

Results

Of the 19 pathogens investigated, the mean number of sero-positive pathogens was 9.4 (SD 1.7), with 24.4% of participants being sero-positive for >10 pathogens. For individual pathogens, the sero-prevalence varied, being for example, 0.05% for HIV, 6.4% f

SUBMITTER: Yao P 

PROVIDER: S-EPMC9086621 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature