Thrombotic Microangiopathy Score as a New Predictor of Neurologic Outcomes in Patients after Out-of-Hospital Cardiac Arrest.

ABSTRACT:

Purpose

Given the morphological characteristics of schistocytes, thrombotic microangiopathy (TMA) score can be beneficial as it can be automatically and accurately measured. This study aimed to investigate whether serial TMA scores until 48 h post admission are associated with clinical outcomes in patients undergoing targeted temperature management (TTM) after out-of-hospital cardiac arrest (OHCA).

Materials and methods

We retrospectively evaluated a cohort of 185 patients using a prospective registry. We analyzed TMA scores at admission and after 12, 24, and 48 hours. The primary outcome measures were poor neurological outcome at discharge and 30-day mortality.

Results

Increased TMA scores at all measured time points were independent predictors of poor neurological o

SUBMITTER: You JS 

PROVIDER: S-EPMC9086697 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature