Characterization and osteogenic evaluation of mesoporous magnesium-calcium silicate/polycaprolactone/polybutylene succinate composite scaffolds fabricated by rapid prototyping.

ABSTRACT: The properties of scaffolds for bone tissue engineering, including their biocompatibility, highly interconnected porosity, and mechanical integrity, are critical for promoting cell adhesion, proliferation, and osteoinduction. We used various physical and biological assays to obtain in vitro confirmation that the proposed composite scaffolds are potentially suitable for applications to bone tissue engineering. The proposed new composite scaffolds, which we fabricated by a rapid prototyping technique, were composed of mesoporous magnesium-calcium silicate (m_MCS), polycaprolactone (PCL), and polybutylene succinate (PBSu). We systematically evaluated the characteristics of the composite scaffolds, such as the hydrophilicity and bioactivity. We also investigated the proliferation and os

SUBMITTER: Kang YG 

PROVIDER: S-EPMC9086718 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature