Bidirectional Relationship Between Body Pain and Depressive Symptoms: A Pooled Analysis of Two National Aging Cohort Studies.

ABSTRACT:

Aims

To investigate the bidirectional longitudinal association between pain and depressive symptoms and explore whether gender modifies the association.

Methods

This study used data of 17,577 participants without depressive symptoms and 15,775 without pain at baseline from waves 1-8 (2002/2003 to 2016/2017) of the English Longitudinal Study of Aging (ELSA) and waves 1 to 3 [2011-2015] of the China Health Retirement Longitudinal Study (CHARLS). Cox regression models were performed at the cohort level to evaluate the potential longitudinal associations, and then random-effect meta-analyses were conducted to pool the results. The potential modifying effect was detected by Z-test.

Results

During 103,512 person-years of follow-up in participants without depressive s

SUBMITTER: Qiu Y 

PROVIDER: S-EPMC9086823 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature