Hippocampus Maintains a Coherent Map Under Reward Feature-Landmark Cue Conflict.

ABSTRACT: Animals predominantly use salient visual cues (landmarks) for efficient navigation. When the relative position of the visual cues is altered, the hippocampal population exhibits heterogeneous responses and constructs context-specific spatial maps. Another critical factor that can strongly modulate spatial representation is the presence of reward. Reward features can drive behavior and are known to bias spatial attention. However, it is unclear whether reward features are used for spatial reference in the presence of distal cues and how the hippocampus population dynamics changes when the association between reward features and distal cues is altered. We systematically investigated these questions by recording place cells from the CA1 in different sets of experiments while the rats ran in a

SUBMITTER: Nair IR 

PROVIDER: S-EPMC9086833 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature