Comparison of Survival Among Adults With Rectal Cancer Who Have Undergone Laparoscopic vs Open Surgery: A Meta-analysis.

ABSTRACT:

Importance

Two large randomized clinical trials (RCTs) found that laparoscopic surgery failed to yield noninferior pathologic outcomes compared with open surgery for patients with rectal cancer. The results raised concerns regarding the effectiveness of the laparoscopic approach for patients with rectal cancer.

Objective

To compare the long-term oncologic outcomes of laparoscopic and open surgery for patients with rectal cancer.

Data sources

PubMed, Web of Science, Embase, and Cochrane Central Register of Controlled Trials were searched from database inception to August 13, 2021. Studies published in English were retrieved.

Study selection

The meta-analysis included RCTs that compared laparoscopic surgery with open surgery for patients with rectal cancer and re

SUBMITTER: Kong M 

PROVIDER: S-EPMC9086842 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature