Persistent Liver Dysfunction in Pediatric Patients After Total Cavopulmonary Connection Surgery.

ABSTRACT:

Background

Studies have reported early liver dysfunction (LD) after cardiac surgery is associated with short and long-term mortality. In this study, we aimed to investigate risk factors for persistent LD after total cavopulmonary connection (TCPC) surgery.

Methods

This is a retrospective case-control study. We defined persistent LD as LDs occurring between postoperative day 1 (POD1) and POD7 and sustaining at least on POD7, while transient LD as LDs occurring between POD1 and POD7 and recovering at least on POD7. Multivariable logistic regression analysis was applied and central venous pressure (CVP) was considered continuously or in quantiles.

Results

Postoperative LD occurred in 111 (27.1%) patients. Transient and persistent LD occurred in 65 (15.9%) and 46 (11.2%)

SUBMITTER: Luo Q 

PROVIDER: S-EPMC9087337 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature