Dataset Information

A snapshot of the prevalence of endocrine disorders in pregnancies complicated by coronavirus disease 2019: A narrative review with meta-analysis.

ABSTRACT:

Background

Some maternal characteristics indicate worse prognosis in pregnant women with coronavirus disease 2019 (COVID-19).

Objective

To describe the prevalence of endocrine disorders in pregnancies involving COVID-19, and its impact on maternal outcomes.

Search strategy

Search terms were "pregnancy" and "COVID-19".

Selection

PubMed, Embase, medRxiv, and Cochrane worksheet from February to July 2020 were searched.

Data collection and analysis

Articles describing endocrine disorders in pregnancies with and without COVID-19 involvement were considered. We performed meta-analyses of prevalence using random-effect models and estimated relative risk and 95% confidence intervals (CI) of maternal outcomes relative to presence of endocrine disorders.

Main results

Articles included (n = 141) were divided into three data sets: individual (119 articles, 356 women), case series (17 articles, 1064 women), and national registries (7 articles, 10 178 women). Prevalence of obesity ranged from 16% to 46% and hyperglycemia in pregnancy (HIP) ranged from 8% to 12%. In data set 1, HIP and obesity were risk factors for severe disease in crude and age-adjusted models, although not for intensive care unit admission. In data from two national registries, risk of dying was 5.62 (95% CI 0.30-105.95) in women with diabetes and 2.26 (95% CI 1.03-4.96) in those with obesity.

Conclusion

Obesity and HIP were prevalent in pregnant women with severe COVID-19.

SUBMITTER: Reichelt AJ

PROVIDER: S-EPMC9087602 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

A snapshot of the prevalence of endocrine disorders in pregnancies complicated by coronavirus disease 2019: A narrative review with meta-analysis.

Reichelt Angela J AJ Hirakata Vânia N VN Genro Vanessa K VK Oppermann Maria Lúcia R MLR

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20210529 2

<h4>Background</h4>Some maternal characteristics indicate worse prognosis in pregnant women with coronavirus disease 2019 (COVID-19).<h4>Objective</h4>To describe the prevalence of endocrine disorders in pregnancies involving COVID-19, and its impact on maternal outcomes.<h4>Search strategy</h4>Search terms were "pregnancy" and "COVID-19".<h4>Selection</h4>PubMed, Embase, medRxiv, and Cochrane worksheet from February to July 2020 were searched.<h4>Data collection and analysis</h4>Articles descri ...[more]

PMID: 33866551

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Dataset Information

A snapshot of the prevalence of endocrine disorders in pregnancies complicated by coronavirus disease 2019: A narrative review with meta-analysis.

Background

Objective

Search strategy

Selection

Data collection and analysis

Main results

Conclusion

Publications

A snapshot of the prevalence of endocrine disorders in pregnancies complicated by coronavirus disease 2019: A narrative review with meta-analysis.

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