MASiVar: Multisite, multiscanner, and multisubject acquisitions for studying variability in diffusion weighted MRI.

ABSTRACT:

Purpose

Diffusion-weighted imaging allows investigators to identify structural, microstructural, and connectivity-based differences between subjects, but variability due to session and scanner biases is a challenge.

Methods

To investigate DWI variability, we present MASiVar, a multisite data set consisting of 319 diffusion scans acquired at 3 T from b = 1000 to 3000 s/mm² across 14 healthy adults, 83 healthy children (5 to 8 years), three sites, and four scanners as a publicly available, preprocessed, and de-identified data set. With the adult data, we demonstrate the capacity of MASiVar to simultaneously quantify the intrasession, intersession, interscanner, and intersubject variability of four common DWI processing approaches: (1) a tensor signal representation,

SUBMITTER: Cai LY 

PROVIDER: S-EPMC9087815 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature