Value of lymphadenectomy in patients with surgically resected pancreatic neuroendocrine tumors.

ABSTRACT:

Background

Although some factors that predict the prognosis in pancreatic neuroendocrine tumor (pNET) have been confirmed, the predictive value of lymph node metastasis (LNM) in the prognosis of pNETs remains conflicting and it is not clear whether regional lymphadenectomy should be performed in all grades of tumors.

Methods

We included pNET patients undergoing surgery in Shanghai pancreatic cancer institute (SHPCI). The risk factors for survival were investigated by the Kaplan-Meier method and Cox regression model. We evaluated the predictors of LNM using Logistic regression.

Results

For 206 patients in the SHPCI series, LNM was an independent prognostic factor for entire cohort suggested by multivariate Cox regression analysis. LNM (P = 0.002) predicted poorer overa

SUBMITTER: Zhang Z 

PROVIDER: S-EPMC9088076 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature