Theoretical and experimental investigation of anticancer activities of an acyclic and symmetrical compartmental Schiff base ligand and its Co(ii), Cu(ii) and Zn(ii) complexes.

ABSTRACT: A compartmental Schiff base ligand, 2,2'-((((((2-hydroxypropane-1,3-diyl)bis(oxy))bis(2,1-phenylene))bis(methylene))bis(azanylylidene))bis(methanylylidene))bis(4-bromophenol) (H₃L^Br) and its complexes with cobalt(ii), copper(ii) and zinc(ii) including, [Co(HL^Br)] (1), [Cu₂(L^Br)(μ-1,3-OAc)]·MeOH (2) and [Zn(HL^Br)] (3) were prepared using template synthesis and characterised by elemental analysis, FT-IR and ¹H NMR spectroscopies and single-crystal X-ray diffraction. In the structure of complexes 1 and 3 the metal atom has a MN₂O₂ environment with tetrahedral geometry while complex 2 has a binuclear structure with a MNO₄ environment and square planar geometry around the copper atom. T

SUBMITTER: Saghatforoush L 

PROVIDER: S-EPMC9088086 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature