Dementia risk in a diverse population: A single-region nested case-control study in the East End of London.

ABSTRACT:

Background

Most evidence about dementia risk comes from relatively affluent people of White European ancestry. We aimed to determine the association between ethnicity, area level socioeconomic deprivation and dementia risk, and the extent to which variation in risk might be attributable to known modifiable clinical risk factors and health behaviours.

Methods

In this nested case-control study, we analysed data from primary care medical records of a population of 1,016,277 from four inner East London boroughs, United Kingdom, collected between 2009 and 2018. The outcome measures were odds ratios for dementia according to ethnicity and deprivation, before and after the addition of major modifiable risk factors for dementia; and weighted population attributable risk for comparis

SUBMITTER: Bothongo PLK 

PROVIDER: S-EPMC9088197 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature