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Multidrug resistant Mycobacterium leprae from patients with leprosy.

ABSTRACT: Sequences of the folP1, rpoB, and gyrA genes were analyzed for 88 isolates of Mycobacterium leprae from leprosy patients in Japan, Haiti, Indonesia, Pakistan, and the Philippines. Thirteen isolates (14.8%) showed representative mutations in more than two genes, suggesting the emergence of multidrug-resistant M. leprae.

SUBMITTER: Maeda S 

PROVIDER: S-EPMC90887 | biostudies-literature | 2001 Dec

REPOSITORIES: biostudies-literature

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Multidrug resistant Mycobacterium leprae from patients with leprosy.

Maeda S S   Matsuoka M M   Nakata N N   Kai M M   Maeda Y Y   Hashimoto K K   Kimura H H   Kobayashi K K   Kashiwabara Y Y  

Antimicrobial agents and chemotherapy 20011201 12

Sequences of the folP1, rpoB, and gyrA genes were analyzed for 88 isolates of Mycobacterium leprae from leprosy patients in Japan, Haiti, Indonesia, Pakistan, and the Philippines. Thirteen isolates (14.8%) showed representative mutations in more than two genes, suggesting the emergence of multidrug-resistant M. leprae. ...[more]

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