Hepatocellular carcinoma surveillance, incidence, and tumor doubling times in patients cured of hepatitis C.

ABSTRACT:

Background

Hepatocellular carcinoma (HCC) incidence and mortality vary by race/ethnicity and both are higher in Black patients than in Whites. For HCC surveillance, all cirrhotic patients are advised to undergo lifelong twice-annual abdominal imaging. We investigated factors associated with surveillance and HCC incidence in a diverse HCC risk group, cirrhotic patients recently cured of hepatitis C virus (HCV) infection.

Methods

In this observational cohort study, all participants (n = 357) had advanced fibrosis/cirrhosis and were cured of HCV with antiviral treatment. None had Liver Imaging Reporting and Data System (LI-RADS) 2-5 lesions prior to HCV cure. Ultrasound, computed tomography, and/or magnetic resonance imaging were used for surveillance.

Results

At a media

SUBMITTER: Perumalswami PV 

PROVIDER: S-EPMC9089228 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature