Late-Onset Alcohol Abuse as a Presenting Symptom of Neurodegenerative Diseases.

ABSTRACT:

Background

The association between lifetime alcohol abuse and a higher risk to develop dementia is well known. However, it is unknown whether older adults who begin abusing alcohol late in life have an underlying neurodegenerative disease.

Objective

Identify the frequency of lifelong alcohol abuse (L-AA), late-onset alcohol abuse (LO-AA), and alcohol abuse as a first symptom of dementia (AA-FS) in patients with neurodegenerative diseases.

Methods

Cross-sectional retrospective study of patients evaluated at an academic referral center with a clinical diagnosis of behavioral variant frontotemporal dementia (bvFTD), Alzheimer-type dementia (AD), and semantic variant primary progressive aphasia (svPPA) (n = 1,518). The presence of alcohol abuse was screened with the Natio

SUBMITTER: de Paula Franca Resende E 

PROVIDER: S-EPMC9090138 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature