A systematic review and meta-analysis of psychological interventions for comorbid post-traumatic stress disorder and substance use disorder.

ABSTRACT:

Background

The psychological treatment of comorbid post-traumatic stress disorder (PTSD) and substance use disorder (SUD) is clinically challenging, and outcomes are often poor.

Objective

This paper describes a systematic review and meta-analysis which sought to establish the current efficacy for a number of established psychological approaches for adults and adolescents, in comparison to interventions for SUD alone, or other active approaches, following a pre-registered protocol.

Method

This review followed PRISMA and Cochrane Collaboration guidelines. Data extraction and risk of bias judgements using Cochrane criteria were undertaken by all authors. Primary outcomes were PTSD severity and substance use post-treatment. The quality of findings was assessed using GRADE

SUBMITTER: Roberts NP 

PROVIDER: S-EPMC9090345 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature