Risk assessment of urban yellow fever virus transmission in Kenya: is Aedes aegypti an efficient vector?

ABSTRACT: The absence of urban yellow fever epidemics in East Africa remains a mystery amidst the proliferation of Aedes aegypti in this region. To understand the transmission dynamics of the disease, we tested urban (Mombasa, Kisumu, and Nairobi) Aedes mosquito populations in Kenya for their susceptibility to an East African yellow fever virus (YFV) genotype. Overall, 22% (n = 805) of the Ae. aegypti that were orally challenged with an infectious dose of YFV had a midgut infection, with comparable rates for Mombasa and Kisumu (χ²= 0.35, df = 1, P = 0.55), but significantly lower rates for Nairobi (χ² ≥ 11.08, df = 1, P ≤ 0.0009). Variations in YFV susceptibility (midgut infection) among Ae. aegypti subspecies were not as

SUBMITTER: Agha SB 

PROVIDER: S-EPMC9090368 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature