Clinical and pathological characteristics of 11 NSCLC patients with c-MET exon 14 skipping.

ABSTRACT:

Background

The aim of the present study was to summarize the clinical and pathological characteristics of 11 non-small cell lung cancer (NSCLC) patients with mesenchymal-epithelial transition factor exon 14 skipping (METex14).

Methods

From 2018 to 2021, medical records of 763 NSCLC patients were reviewed and 11 patients carrying METex14 were identified from the Affiliated Hospital of Guangdong Medical University. Their clinical data were subsequently examined for pathological and related clinical information including symptom and diagnosis, imaging and follow-up.

Results

The METex14 cohort includes 9 males and 2 females and the age range was 69-85 years, with a median age of 77 years. Of the patients one is diagnosed with stage IVB lung adenosquamous carcinoma, 7 with

SUBMITTER: Chen H 

PROVIDER: S-EPMC9091003 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature