High expression of C10orf91 and LINC01224 in hepatocellular carcinoma and poor prognosis.

ABSTRACT:

Background

The dysregulation of long non-coding RNAs (lncRNAs) has been implicated roles in the pathogenesis of many human diseases, including hepatic diseases. Several lncRNAs have been associated with the progression of hepatocellular carcinoma (HCC), but their function as diagnostic markers for liver cancer remain to be determined.

Objective

This study aimed to identify the potential diagnostic markers for liver cancer.

Methods

The Cancer Genome Atlas (TCGA) database was used to obtain the gene transcriptome data of liver cancer. In addition, this study enrolled 70 liver cancer patients admitted to the Yiwu Central Hospital and 50 healthy people who concurrently underwent physical examinations from February 2017 to January 2020. Quantitative reverse transcription p

SUBMITTER: Gong A 

PROVIDER: S-EPMC9091127 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature