Circadian Clock Genes Regulate Temperature-Dependent Diapause Induction in Silkworm Bombyx mori.

ABSTRACT: The bivoltine strain of the domestic silkworm, Bombyx mori, exhibits a facultative diapause phenotype that is determined by maternal environmental conditions during embryonic and larval development. Although a recent study implicated a circadian clock gene period (per) in circadian rhythms and photoperiod-induced diapause, the roles of other core feedback loop genes, including timeless (tim), Clock (Clk), cycle (cyc), and cryptochrome2 (cry2), have to be clarified yet. Therefore, the aim of this study was to elucidate the roles of circadian clock genes in temperature-dependent diapause induction. To achieve this, per, tim, Clk, cyc, and cry2 knockout (KO) mutants were generated,

SUBMITTER: Homma S 

PROVIDER: S-EPMC9091332 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature