A genome-wide test for paternal indirect genetic effects on lifespan in Drosophila melanogaster.

ABSTRACT: Exposing sires to various environmental manipulations has demonstrated that paternal effects can be non-trivial also in species where male investment in offspring is almost exclusively limited to sperm. Whether paternal effects also have a genetic component (i.e. paternal indirect genetic effects (PIGEs)) in such species is however largely unknown, primarily because of methodological difficulties separating indirect from direct effects of genes. PIGEs may nevertheless be important since they have the capacity to contribute to evolutionary change. Here we use Drosophila genetics to construct a breeding design that allows testing nearly complete haploid genomes (more than 99%) for PIGEs. Using this technique, we estimate the variance in male lifespan due to PIGEs among four population

SUBMITTER: Shenoi VN 

PROVIDER: S-EPMC9091837 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature