Antiplatelet Therapy in Atherothrombotic Diseases: Similarities and Differences Across Guidelines.

ABSTRACT: Antiplatelet therapy, mainly consisting of aspirin and P2Y₁₂ receptor antagonists, is the cornerstone of the pharmacological treatment and prevention of atherothrombotic diseases. Its use, especially in secondary cardiovascular prevention, has significantly improved patient clinical outcomes in the last decades. Primary safety endpoint (i.e., bleeding complications) remain a major drawback of antiplatelet drugs. National and international societies have published and regularly updated guidelines for antiplatelet therapy aiming to provide clinicians with practical recommendations for a better handling of these drugs in various clinical settings. Many recommendations find common ground between international guidelines, but certain strategies vary across the countries, particularly

SUBMITTER: Jourdi G 

PROVIDER: S-EPMC9092185 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature