PET/CT Based EGFR Mutation Status Classification of NSCLC Using Deep Learning Features and Radiomics Features.

ABSTRACT: Purpose: This study aimed to compare the performance of radiomics and deep learning in predicting EGFR mutation status in patients with lung cancer based on PET/CT images, and tried to explore a model with excellent prediction performance to accurately predict EGFR mutation status in patients with non-small cell lung cancer (NSCLC). Method: PET/CT images of 194 NSCLC patients from Xijing Hospital were collected and divided into a training set and a validation set according to the ratio of 7:3. Statistics were made on patients' clinical characteristics, and a large number of features were extracted based on their PET/CT images (4306 radiomics features and 2048 deep learning features per person) with the pyradiomics toolkit and 3D convolutional neural network. Then a radiomics

SUBMITTER: Huang W 

PROVIDER: S-EPMC9092283 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature