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Synthesis of mixed musks via Eschenmoser-Tanabe fragmentation, enyne metathesis and Diels-Alder reaction as key steps.


ABSTRACT: Musk analogues containing different macrocyclic ring systems as well as different annulated ring systems were synthesised by a simple and useful strategy. This strategy includes Eschenmoser-Tanabe fragmentation, enyne metathesis and Diels-Alder reaction as key steps. Starting from easily available (n) macrocyclic ketones, (n + 3) macrocyclic systems were assembled using the basic organic reactions.

SUBMITTER: Kotha S 

PROVIDER: S-EPMC9092383 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature