Amberlite-15 promoted an unprecedented aza Michael rearrangement for one pot synthesis of dihydroquinazolinone compounds.

ABSTRACT: A new one pot multicomponent annulation strategy for the synthesis of various dihydroquinazolinone compounds has been developed using Amberlite-15 as a catalyst, giving good to moderate yields. In this reaction the substrate scope for amines and aldehydes was also investigated. The reaction has been checked on a large scale and the possible reaction mechanism has also been proposed.

SUBMITTER: Murthy VN 

PROVIDER: S-EPMC9092434 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature