Nickel(ii)-catalyzed tandem C(sp²)-H bond activation and annulation of arenes with gem-dibromoalkenes.

ABSTRACT: A nickel(ii)/silver(i)-catalyzed tandem C(sp²)-H activation and intramolecular annulation of arenes with dibromoalkenes has been successfully achieved, which offers an efficient approach to the 3-methyleneisoindolin-1-one scaffold. Attractive features of this system include its low cost, ease of operation, and its ability to access a wide range of isoindolinones.

SUBMITTER: Shi Y 

PROVIDER: S-EPMC9092601 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature