Characteristics of acute kidney injury and its impact on outcome in patients with acute-on-chronic liver failure.

ABSTRACT:

Objective

Acute kidney injury (AKI) is a common and life-threatening complication of liver failure. The purpose of this study is to construct a nomogram and online calculator to predict the development of hospital-acquired acute kidney injury (HA-AKI) in patients with acute-on-chronic liver failure (ACLF), which may contribute to the prognosis of ACLF.

Methods

574 ACLF patients were evaluated retrospectively. AKI was defined by criteria proposed by International Club of Ascites (ICA) and divided into community-acquired and hospital-acquired AKI (CA-AKI and HA-AKI). The difference between CA-AKI and HA-AKI, factors associated with development into and recovered from AKI periods. The risk factors were identified and nomograms were developed to predict the morbidity of HA-AKI i

SUBMITTER: Huang Y 

PROVIDER: S-EPMC9092688 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature