Case of a Man with Hemichorea and Behavioral Changes: "A Red Herring".

ABSTRACT:

Background

Progressive supranuclear palsy (PSP)-pallido-nigro-luysian atrophy (PNLA) is a neuropathological entity thought to be a variant of classic PSP. Clinical features and pathologic hallmarks are the same in both conditions; however, age and order of symptom onset, disease duration and prognosis, and distribution and density of pathology differentiate the 2 entities.

Objectives

This study presents a PSP-PNLA case confirmed pathologically with a clinical presentation of hemichorea/ballism, spasticity, progressive hemiparesis, and a frontal behavioral syndrome with relative cognitive sparing early in the disease course.

Methods

We describe the clinical progression in this unique case supplemented with video and imaging findings in the form of magnetic resonance im

SUBMITTER: Kleiner G 

PROVIDER: S-EPMC9092749 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature