Von Willebrand disease and von Willebrand factor.

ABSTRACT: Progress in both basic and translational research into the molecular mechanisms of VWD can be seen in multiple fields.

Genetics of vwd

In the past several decades, knowledge of the underlying pathogenesis of von Willebrand disease (VWD) has increased tremendously, thanks in no small part to detailed genetic mapping of the von Willebrand Factor (VWF) gene and advances in genetic and bioinformatic technology. However, these advances do not always easily translate into improved management for patients with VWD and low-VWF levels.

Vwd and pregnancy

For example, the treatment of pregnant women with VWD both pre- and postpartum can be complicated. While knowledge of the VWF genotype at some amino acid positions can aid in knowledge of who may be at increased risk of thrombocytopeni

SUBMITTER: Sadler B 

PROVIDER: S-EPMC9094051 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature