Late non-fasting plasma glucose predicts cardiovascular mortality independent of hemoglobin A1c.

ABSTRACT: It is unknown whether non-fasting plasma glucose (PG) is associated with cardiovascular disease (CVD) mortality. This study aimed to investigate this association in US adults. This study included adults from the National Health and Nutrition Examination Surveys from 1988 to 2014. Mortality outcomes were ascertained by linkage to the National Death Index records. Cox proportional hazards models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) of PG for CVD mortality. Among 34,907 participants, 1956, 5564, and 27,387 had PG from participants in early non-fasting, late non-fasting, and fasting states, respectively (defined as a period since last calorie intake of 0-2.9, 3.0-7.9, or ≥ 8.0 h, respectively). This cohort was followed up for 455,177 person-years (mean f

SUBMITTER: Wang Y 

PROVIDER: S-EPMC9095589 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature