Incubation period, clinical and lung CT features for early prediction of COVID-19 deterioration: development and internal verification of a risk model.

ABSTRACT:

Background

Most severe, critical, or mortal COVID-19 cases often had a relatively stable period before their status worsened. We developed a deterioration risk model of COVID-19 (DRM-COVID-19) to predict exacerbation risk and optimize disease management on admission.

Method

We conducted a multicenter retrospective cohort study with 239 confirmed symptomatic COVID-19 patients. A combination of the least absolute shrinkage and selection operator (LASSO), change-in-estimate (CIE) screened out independent risk factors for the multivariate logistic regression model (DRM-COVID-19) from 44 variables, including epidemiological, demographic, clinical, and lung CT features. The compound study endpoint was progression to severe, critical, or mortal status. Additionally, the model's per

SUBMITTER: Peng H 

PROVIDER: S-EPMC9095818 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature