Deep learning acceleration of multiscale superresolution localization photoacoustic imaging.

ABSTRACT: A superresolution imaging approach that localizes very small targets, such as red blood cells or droplets of injected photoacoustic dye, has significantly improved spatial resolution in various biological and medical imaging modalities. However, this superior spatial resolution is achieved by sacrificing temporal resolution because many raw image frames, each containing the localization target, must be superimposed to form a sufficiently sampled high-density superresolution image. Here, we demonstrate a computational strategy based on deep neural networks (DNNs) to reconstruct high-density superresolution images from far fewer raw image frames. The localization strategy can be applied for both 3D label-free localization optical-resolution photoacoustic microscopy (OR-PAM) and 2D labeled lo

SUBMITTER: Kim J 

PROVIDER: S-EPMC9095876 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature