The Extensive Regulation of MicroRNA in Immune Thrombocytopenia.

ABSTRACT: MicroRNA (miRNA) is a small, single-stranded, non-coding RNA molecule that plays a variety of key roles in different biological processes through post-transcriptional regulation of gene expression. MiRNA has been proved to be a variety of cellular processes involved in development, differentiation, signal transduction, and is an important regulator of immune and autoimmune diseases. Therefore, it may act as potent modulators of the immune system and play an important role in the development of several autoimmune diseases. Immune thrombocytopenia (ITP) is an autoimmune systemic disease characterized by a low platelet count. Several studies suggest that like other autoimmune disorders, miRNAs are deeply involved in the pathogenesis of ITP, interacting with the function of innate and adaptive

SUBMITTER: Zhao Y 

PROVIDER: S-EPMC9096216 | biostudies-literature | 2022 Jan-Dec

REPOSITORIES: biostudies-literature