Probiotics for the Management of Infectious Diseases: Reviewing the State of the Art.

ABSTRACT: This review aims to provide insight into the potential of probiotics as a clinical modality targeted at infectious diseases by creating a comprehensive overview of the state of the art of research and development efforts as shown by patents and clinical trials of the past 20 years. Data were retrieved from patent and clinical trial databases to reflect the long- and short-term developments of probiotics research. The data were analyzed to extract information on the total number of patents and trials for each indication, application date and location, and applicant/sponsor type. A total of 80 infectious diseases were investigated, precipitating in 789 patents and 602 clinical trials for 67 indications studied as targets of probiotics. An increasing trend was seen for the number of patents a

SUBMITTER: Wiegers C 

PROVIDER: S-EPMC9096241 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature