Clinical significance of tumor necrosis and viability in non-small cell lung cancer.

ABSTRACT:

Background

We included tumor necrosis (TN) and tumor viability (TV) in our prognostic assessment of patients with non-small cell lung cancer (NSCLC) and investigated their clinical significance.

Methods

Medical records of all consecutive subjects who underwent a lobectomy with standard mediastinal lymph node dissection for NSCLC between 2015 to 2016, were reviewed retrospectively. We analyzed the associations of TN and TV with various parameters associated with prognosis as well as survival in NSCLC patients. All analyses were performed regarding neoadjuvant therapy status [the group without neoadjuvant therapy (WON) vs. the group with neoadjuvant therapy (WN)].

Results

A consecutive 154 patients (mean age: 65.0±10.1 years) were included into the present study.

SUBMITTER: Moon SW 

PROVIDER: S-EPMC9096282 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature